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Professor Phil Hodgkin has helped transform understanding of immune regulation with innovative theories and novel experimental approaches. His mathematical models of immune responses are foundational for the SCIH.
Phil’s research is focussed on the problem of how immune cells process information and regulate outcomes. This has required inventing methods for integrating molecular and cellular dynamics to make predictions of immune function at multiple scales. Phil is the former President of the Australian and New Zealand Society for Immunology.
Phil is recognised as one of the pioneers of systems immunology.
Expertise
Professor Jo Douglass is a globally recognised allergy and respiratory physician. Jo is the James Stewart Professor of Medicine and Head of the Department of Medicine in the Melbourne Medical School. She also holds the position of Director of Research at the Royal Melbourne Hospital.
From 2012 to 2020, Jo was head of The Department of Immunology and Allergy at the Royal Melbourne Hospital. She is an active clinician with clinical practice and teaching in asthma, especially severe asthma, allergic diseases, and Immune Deficiencies. She is an active researcher with current funded projects in severe asthma, especially Thunderstorm asthma and practice in the genomics of immune deficiencies alongside collaborators at WEHI. She is widely published, with over 100 original publications.
Jo is the former President of the Australasian Society of Clinical Immunology and Allergy.
Expertise
Dr Vanessa Bryant‘s team most recently discovered novel causes of rare antibody deficiencies that have directly led to therapeutic intervention and personalised care for children and adults with immunodeficiency.
Vanessa leads the Victorian Node of the recently established MRFF-funded Australian Alliance for Indigenous Genomics (ALIGN) and co-leads the MRFF-funded Australian ImmunoGenomics Network with Stuart Tangye (Garvan). She previously co-led the successful Melbourne Genomics Immunology Flagship Program and Antibody Deficiency Program of Australian Genomics Genetic Immunology.
Vanessa’s skills provide a fundamental molecular and cellular foundation that synergises with clinical pathways of diagnosis and care.
Expertise
Dr Charlotte Slade is clinician scientist who has discovered new genetic disorders and delivered precision care for patients living with rare immune disorders.
Charlotte brings a unique strength and diversity to the team, as both the Clinical immunologist, the Royal Melbourne Hospital and a Laboratory Head at WEHI. In these combined roles, she is uniquely placed to dedicate her career to defining sources of immune dysfunction and designing personalised therapies.
Expertise
Professor Daniel Gray’s team employs new genetic, single-cell, and imaging-based technologies to address how the immune system makes decisions in the context of autoimmune disease, infection, and cancer.
Daniel’s contributions have come through a mixture of large, collaborative, consortia-based research programs, as well as more focused, hypothesis-driven projects to make fundamental discoveries with translational impact. He is an international leader in how cell death processes impact T cell responses and immunological tolerance: key goals of the modelling of molecular networks program.
Expertise
Professor Stephen Nutt is Fellow of the Australian Academy of Science and a world-leading expert in molecular immunology. He is a member of the international Immunological Genome Consortium.
Steve has made significant discoveries relating to the transcriptional processes required for immune cell development and differentiation. Steve’s research focuses on understanding how gene regulatory networks control cellular decisions in the immune system and how to target these processes with new therapeutic approaches. His leadership in these domains will propel the molecular networks and drug discovery programs of the SCIH.
Expertise